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When ionotropic receptors are activated, certain ion species such as Na to enter the postsynaptic neuron, which depolarizes the postsynaptic membrane.
If more of the same type of postsynaptic receptors are activated, then more Na will enter the postsynaptic membrane and depolarize cell.
When there is a change in voltage in the terminal bouton, voltage-gated calcium channels embedded in the membranes of these boutons become activated.
These allow Ca2 ions to diffuse through these channels and bind with synaptic vesicles within the terminal boutons.
There are two families of receptors: ionotropic and metabotropic receptors.
Since memories are postulated to be represented by vastly interconnected networks of synapses in the brain, synaptic plasticity is one of the important neurochemical foundations of learning and memory (see Hebbian theory).Some neurons such as photoreceptor cells, for example, do not have myelinated axons that conduct action potentials.